We use cookies to ensure that we give you the best experience on our website. If you continue browsing our
website without changing your settings, we will assume that you are happy to receive all cookies on our site.

You can visit our Cookie Policy page to learn more about cookies and how to disable them, should you wish to withdraw your consent. Our Cookie Policy page explains what cookies are, lists the cookies used on this website, and outlines how you can manage them.

Subscribe to our regular email newsletter

Before you go...

Please give us your feedback on our site:

How useful was the site to
you today?

Written by

Professor Madelon L Peters Professor Madelon L Peters is professor of experimental health psychology, Maastricht University, The Netherlands

The biopsychosocial model and chronic pain – an overview

Published 1 December 2015

The biopsychosocial approach to pain, which addresses psychological and social aspects, is widely accepted as essential for the management of chronic pain, writes Professor Madelon Peters

Key learning points

  • The biopsychosocial approach to pain addresses psychological and sociocultural factors in addition to biomedical/physiological aspects.
  • Emotions, catastrophising, expectancy and sociocultural context can all influence the course and treatment of chronic pain and should be addressed.
  • Chronic pain states are complex disorders and a biopsychosocial approach is mandatory.
  • Treatment can range from initial low-intensity interventions delivered in primary care to complex multidisciplinary pain treatment in a specialised setting.

Chronic pain is a disorder characterised by complex interactions between physiological, psychological and sociocultural factors. The biopsychosocial approach to pain acknowledges the multiple influences that shape the conscious experience of pain and that determine its clinical presentation. Assessment and management of chronic pain should therefore go beyond purely biomedical approaches to address the various issues with which a patient with chronic pain may be struggling.

Affective dimension of chronic pain

Chronic pain is often associated with negative emotions. As many as 50% of patients with chronic pain have a co-morbid depressive disorder.1 Concurrent depressive symptoms in patients with chronic pain are associated with increased disability and augmented pain experience.2 Anxiety is another negative emotion frequently seen in patients with chronic pain, and which may lead to maladaptive pain behaviours aggravating and maintaining pain and disability.3

Healthcare providers should be aware of and deal with these and other negative emotions because they affect the wellbeing of patients, worsen pain and can impact on treatment success.

Cognitive dimension of chronic pain

Cognitive states also influence pain perception and associated disability and require attention. In particular, pain catastrophising, which is defined as an exaggerated negative appraisal of pain and its possible consequences, has shown robust associations with more intense pain, more interference by pain and more disability in patients with chronic pain.4

Expectancies are another major factor influencing the course of pain as well as treatment efficacy. Negative expectancies regarding the persistence of pain, disability and ability to work may lead to a self-fulfilling prophecy.5 Furthermore, negative expectancies about the effects of treatment may reduce its efficacy in reality.6

The sociocultural context of chronic pain

Finally, how people perceive and deal with pain is also shaped by the sociocultural context. Modelling of pain behaviour by parents or significant others, as well as operant learning processes, affect pain and pain behaviour.7 Verbal and behavioural pain expressions may be reinforced by the attention and sympathy they elicit from others. Cultural factors may affect how pain is expressed, and there are cultural differences in the meaning of pain and treatment-seeking.8 Insensitivity to cultural differences can result in ineffective patient–healthcare provider communication and inadequate pain management.

Biopsychosocial assessment of pain

A biopsychosocial treatment approach to chronic pain takes the dynamic interplay between physiological, psychological, social and cultural factors into account. Consequently, all healthcare providers involved in treating a patient with chronic pain should not only evaluate a patient from a purely biological perspective but also consider the psychological and social dimensions as well. Only after proper multidimensional evaluation can an effective treatment plan be developed that addresses the specific needs of a patient.

Implications of the biopsychosocial approach for treatment

For patients with long-standing and complex pain complaints where multiple issues surrounding their pain problem are identified, multidisciplinary pain treatment may be indicated. Such treatments target a broad range of factors and combine physical, educational and psychological intervention strategies. Multidisciplinary pain treatments are usually delivered in specialised pain clinics or rehabilitation centres.

Although multidisciplinary interventions are the treatment of choice for patients with complex pain issues, they are also time consuming and costly. Therefore a stepped-care approach has been advocated with low intensity interventions offered as a first step, usually in primary care, and more intensive and costly treatments in specialised treatment centres only when a patient does not sufficiently benefit from initial interventions.9

Regardless of the intensity and site of treatment, a biopsychosocial perspective towards chronic pain management is always imperative.

  • Professor Madelon L Peters is professor of experimental health psychology, Maastricht University, The Netherlands

Further reading and resources

Gatchel RJ, Peng YB, et al. The biopsychosocial approach to chronic pain: scientific advances and future directions. Psychological Bulletin 2007;133(4):581–624.

Peters ML. Emotional and cognitive influence on pain experience. In: Finn DP, Leonard BE (editors): Pain in Psychiatric Disorders. Modern Trends in Pharmacopsychiatry. Volume 30. Basel, Karger, 2015.

Flor H, Turk DC. Chronic Pain: An Integrated Biobehavioral Approach. Philadelphia, Lippincott Williams & Wilkins, 2011.

Kamper SJ, Apeldoorn AT, et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain. Cochrane Database of Systematic Reviews 2014, Issue 9. Art No: CD000963.

Practical Pain Management

IASP Pain: Clinical Updates


  1. Bair MJ, Robinson RL, et al. Archives of Internal Medicine 2003;163(20):2433–2445.
  2. Gaskin, ME, Greene AF, et al. Journal of Psychosomatic Research 1992;36(8):707–713.
  3. Vlaeyen JW, Linton SJ. Pain 2012;153(6):1144–1147.
  4. Quartana PJ, Campbell CM, et al. Expert Review of Neurotherapeutics 2009;9(5):745–758.
  5. Johansson AC, Linton SJ, et al. Disability and Rehabilitation 2010;32(7):521–529.
  6. Klinger R, Colloca L, et al. Pain 2014;155(6):1055–1058.
  7. Goubert L, Vlaeyen JW, et al. The Journal of Pain 2011;12(2):167–174.
  8. Shipton EA. The New Zealand Medical Journal 2013;126(1370):7–9.
  9. Rosenberger PH, Kerns R. Annals of Behavioral Medicine 2012;43:S265.

Date of preparation: November 2015; MINT/PAEU-15019